The Science Behind the Seeds

The ongoing study of seeds and their power leads to beneficial, efficacious products.

Cranberry seeds spilling out of a petri dish

The Science Behind the Seeds

The ongoing study of seeds and their power leads to beneficial, efficacious products.

Continuous Discovery & Innovation

We are continually exploring new uses and applications for our products and formulations. In doing so, we partner with a vast network of academic institutions, medical doctors and nutrition scientists. Our esteemed collaborators work closely with us to identify and validate product benefits and nutrient profiles.

Partners and research initiatives include:

University of Minnesota Medical School – Seed oils Anti-inflammatory affects

University of Wisconsin-Oshkosh – Anti-viral properties and Biochemical Characteristics of Cranberry extract

University of Maryland – Biochemical characteristics and synergistic antioxidant activity of cold pressed seed oils

Colorado State University – Oxidative Stability of Cold Pressed Oils

Oregon State University – Biochemical Characteristics of Cranberry Seeds and Oils

Super Potent Antioxidant Patent

US Patent No. 7,897,194 B2

Botanic Innovations holds the U.S. patent for “Synergistic Super Potent Antioxidant Cold Pressed Botanic Oil Blends.

The “Black Cumin Seed Oil Synergy Patent” covers the synergistic effect of antioxidant activity that occurs when Botanic Innovations cold pressed Black Cumin Seed Oil is blended with any other Botanic Innovations cold pressed seed oil (including Red Raspberry Seed Oil, Cranberry Seed Oil, and Black Raspberry Seed Oil among many others).

The antioxidant level after blending exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.

This means that blends made with Black Cumin Seed Oil are truly synergistic! These blends provide antioxidant levels greater than the sum total of each of the individual oils. Products made with any of our Black Cumin Seed Oil blends boast these same antioxidant benefits.

The patent encompasses both the synergistic effect of antioxidant activity when used topically and/or when ingested, making Black Cumin Seed Oil, combined with additional Botanic Innovations seed-oils, a powerful component within supplements, topical cosmeceuticals, and personal care products. The blends provide antioxidant levels greater than the sum of antioxidants within each of the individual oils.

Our synergy patent (US PTO number 7,897,154 B2) describes a method to create the experience of antioxidant synergistic properties by using black cumin seed oil and combining it with or formulating it into a blend with separate cold-pressed oils. Synergy is measured in vitro where the total antioxidant value of the blend or formulation is greater than the sum of the antioxidant values of the individual oils that make up the formulation, as measured by Trolox Equivalents (Vitamin E) /Liter.

Ongoing Investigation

Our seed oils, powders, and blends have been the subject of 15+ years of ongoing scientific study and research, driven by Botanic Innovations. The physical and chemical characteristics of our products have been investigated and reported in many peer reviewed scientific and medical publications.

These studies include:

  • Antioxidants Benefit Diastolic Pressure, CRP2 and Lipids in Adult
    Arnold S Leonard MD PhD 1,Tim Hammer DC MPH 2, Rachel Moor 2, Richard Grimm PhD 2, Mark Mueller 3, Paul Addis PhD 3, John A St.Cyr, Daniel Saltzman MD PhD 1, 1 University of Minnesota, Mpls, MN, 2 Berman Center, Mpls, MN; 3 Botanic Oils Innovations, Spooner, WI.
  • Creation of Super Potent Antioxidant Values through Synergy of Cold Pressed Botanic Oils for Therapeutic Purposes
    Arnold S. Leonard MD, PhD, Daniel Saltzman, MD, PhD, Mark Mueller, Naturopathy Digest.
  • Effects of Different Cold Extracted Botanical Lipids on the Expression of Genes in Senescent Fibroblast, an Analysis of Gene Expression Using Desiccated cDNA Arrays
    BIO alternatives Laboratory, Gencay France. Alain Deguercy, PhD. Arnold Leonard, MD, PhD, Daniel Saltzman, MD, PhD, Mark Mueller.
  • Evaluation and Summary of the Anti-inflammatory and Anti-Stress Effects of Cold Extracted Botanical Lipids Compounds in Cultures of Reconstructed Epidermis
    BIOalternatives Laboratory, Gencay France, Alain Deguercy, PhD. Arnold Leonard, MD, PhD, Daniel Saltzman, MD, PhD, Mark Mueller. “confidential”
  • Use Of Cold-Pressed Edible Seed Oils, Flours, And/or Blends Thereof As Anti-Inflammatory And COX-2 Inhibitory Agents
    Liangli Yu, et.al University of Maryland, Mark Mueller, unpublished.
  • Inhibitory Effect of Chardonnay and Black Raspberry Seed Extracts on Lipid Oxidation in Fish Oil and Their Radical Scavenging and Antimicrobial Properties
    Marla Luther, et. al., University of Maryland Journal of Food Chemistry
  • Oxidative Stability of Fish Oil Enriched with Cold Extracted Black Cumin Seed Oil
    Liangli Yu, PhD., et. al. University of Maryland. “confidential”
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