Cognitive Support Powder Blend

Our Cognitive Support Formula is made with blueberry and grape seed powders, utilized for their antioxidant properties to help support brain function. Antioxidant properties from blueberry and grape seed powders make this blend ideal for functional food and cognitive supplement formulations. Recommended inclusion 40% – 50%.

Ingredient List: Grape (Vitis vinfera) Seed Powder and Blueberry (Vaccinium corymbosum) Seed Powder


Dietary Supplement
Functional Foods
Minimum order 50 lbs


1 lb
SKU: FL-CSPB-lb Category:

Request a quote for any blended seed oils or powders.

Product Benefits

Studies suggest that ingredients with antioxidant properties help support brain function.

Our Cognitive Support Formula, which helps support brain function, is high in catechins, powerful antioxidants that are in the flavonoid family of antioxidants. Catechins are broken down into secondary metabolites by the gut microbiome, these secondary metabolites can easily cross the blood-brain barrier to impart neurocognitive benefits. Catechins have been found to protect neurons from oxidative damage as well as other forms of injury. Catechins also have demonstrated potential for accelerating neurite sprouting.1

Catechins have been shown to improve cognition in mice and humans, in both pre-clinical and clinical studies.2

Catechins in our brain support formula also help improve the dilation of blood vessels and increase blood flow. In this way, the improved blood flow to the brain may improve nutrient and oxygen delivery and help boost mental energy and cognition.3

Cognitive Support Formula, good for cognitive supplements that support brain function, is also high in flavonoids quercetin and kaempferol. Quercetin has been shown to be a neuroprotectant and a cognition booster.4

Quercetin has also been shown to boost mitochondrial production in brain cells. Mitochondria are responsible for the production of the cell’s energy, and brain cells are required to produce massive amounts of energy, this increase in mitochondrial production may be the mechanism behind quercetin’s cognition-boosting effect.5

Cognitive Support Formula consists of 26.2 mg/kg of Polyphenols and consists of 10.2% proanthocyanidins. Polyphenols and proanthocyanidins have been found to be highly neuroprotective.6

Experimental and clinical studies have shown that proanthocyanidins have a variety of pharmacological effects, including potent anti-inflammatory and antioxidant effects.7

Research has demonstrated that proanthocyanidins may be a potential therapeutic agent for some neuroinflammatory diseases, such as mood disorders and Alzheimer’s disease.8

Our Cognitive Support Formula is created using a blend of de-fatted seed powders from the NatureFRESH™ cold-press process and blended to leverage diverse and dense nutrients.

Product Attributes

The oils and powders produced at Botanic Innovations’ are from non-GMO fruit, herb, and vegetable seeds based on our quality assurance practices.

The oils and powders produced at Botanic Innovations do not contain, nor come in contact with, animal products and are qualified as vegan.

All of our ingredients are derived from herb, vegetable, and fruit seeds.

All of our products are certified annually by EarthKosher.

All of our products do not contain artificial ingredients or preservatives and the ingredients are only minimally processed.

All of our products are produced and packaged in the U.S.A.

All of our products are free of animal fats & oils and contain no nuts (including oil & derivatives).


  1. Unno, K.; Pervin, M.; Nakagawa, A.; Iguchi, K.; Hara, A.; Takagaki, A.; Nanjo, F.; Minami, A.; Nakamura, Y. Blood-brain barrier permeability of green tea catechin metabolites and their neuritogenic activity in human neuroblastoma SH-SY5Y cells. Mol. Nutr. Food Res. 2017, 61, 1700294. [CrossRef] [PubMed]
  2. de la Torre, R.; de Sola, S.; Farré, M.; Xicota, L.; Cuenca-Royo, A.; Rodriguez, J.; León, A.; Langohr, K.; Gomis-González, M.; Hernandez, G.; et al. A phase 1, randomized double-blind, placebo controlled trial to evaluate safety and efficacy of epigallocatechin-3-gallate and cognitive training in adults with Fragile X syndrome. Clin. Nutr. 2019
  3. EFSA Panel on Dietetic Products, Nutrition and Allergies (2012). “Scientific opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006”. EFSA Journal. 10 (7): 2809. doi:10.2903/j.efsa.2012.2809.
  4. Alexander SP. Flavonoids as antagonists at A1 adenosine receptors. Phytother. Res. 2006; 20:1009Y12.
  5. Davis JM, Murphy EA, Carmichael MD, Davis B. Quercetin increases and muscle mitochondrial biogenesis and exercise tolerance. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009; 296:R1071Y7.
  6. K.E. Strathearn, G.G. Yousef, M.H. Grace, S.L. Roy, M.A. Tambe, M.G. Ferruzzi, Q.-L. Wu, J.E. Simon, M.A. Lila, J.-C. Rochet, Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson’s disease, BrainRes. 1555 (2014) 60–77.
  7. Uchida, S., Hirai, K., Hatanaka, J., Hanato, J., Umegaki, K., Yamada, S., 2008. Antinociceptive effects of St. John’s wort, Harpagophytum procumbens extract and grape seed proanthocyanidins extract in mice. Biol. Pharm. Bull. 31, 240–245.
  8. Aruoma, O.I., Sun, B., Fujii, H., Neergheen, V.S., Bahorun, T., Kang, K.S., Sung, M.K.,2006. Low molecular proanthocyanidin dietary biofactor oligonol: its modulation of oxidative stress, bioefficacy, neuroprotection, food application and chemoprevention potentials. Biofactors 27 (1–4), 245–265.

Data Sheets